Cheesy Chicken Spaghetti – Creamy, Comforting, and Packed with Southern Flavor!
This dish is a cheesy, creamy hug in a casserole dish. My aunt used to make this every Sunday, and no matter how full we were, there was never a spoonful left. It’s the kind of comfort food that feels like home with every bite.
Ingredients
- 2 cups cooked and shredded chicken
- 8 oz uncooked spaghetti
- 1 can (10.5 oz) cream of chicken soup
- 1 can (10 oz) Rotel (diced tomatoes with green chilies)
- 1 cup sour cream
- 2 cups shredded cheddar cheese
- 1 tsp garlic powder
- ½ tsp onion powder
- Salt and pepper to taste
- 2 tbsp butter
Instructions
Cook spaghetti according to package instructions; drain and set aside.
In a large skillet, melt butter and stir in garlic powder and onion powder.
Add the cream of chicken soup, Rotel, and sour cream to the skillet. Stir until combined.
Mix in the shredded chicken and 1½ cups of the cheese.
Add cooked spaghetti and stir to coat evenly.
Transfer the mixture to a greased baking dish and sprinkle the remaining cheese on top.
Bake at 350°F (175°C) for 25 minutes or until hot and bubbly.
Let rest for 5 minutes before serving.
Nutrition Facts
| Nutrient | Amount Per Serving |
|---|---|
| Calories | 410 kcal |
| Protein | 25 g |
| Carbohydrates | 28 g |
| Fat | 22 g |
| Sodium | 670 mg |
Printable Summary
| Cheesy Chicken Spaghetti Summary | |
|---|---|
| Ingredients | Chicken, spaghetti, cream of chicken soup, Rotel, sour cream, cheddar cheese, garlic & onion powder, butter |
| Instructions | Cook pasta, mix with creamy sauce and chicken, add cheese, bake until bubbly, let rest before serving. |
FAQs
Can I use rotisserie chicken?
Yes, it works perfectly and saves time too!
Is there a substitute for Rotel?
You can use diced tomatoes and a bit of green chili separately.
Can I freeze this?
Yes, assemble it and freeze before baking. Bake from frozen at 375°F for 45–50 minutes.
What cheese works best?
Sharp cheddar is classic, but Monterey Jack or Colby blend nicely too.
